There is a lot of hype around Silverlight and WPF enabling true separation of developer and designer. This is certainly a great way to work. However, I don't think this is enabled only now by XAML. There is no reason the same cannot be achieved with HTML.

It seems like developers went so far down the server-side HTML generation route we left designers floundering with only CSS left in their toolkit. Whilst you can do some amazing things with CSS, sometimes you just need to change the HTML. If the HTML is riddled with <% %>, server controls or other template commands how is out poor designer going to work with the file?

My current attention is around using pure HTML and putting all dynamic content generation into JavaScript. The only thing to enforce on the HTML is that certain elements have known "id" attribute values.